Brain Health,
Sci + Society,

#080: Addiction

June 12, 2015

This week, Jesse talks about addiction with Dr. Jeremy Martinez.

Could a smart drug “habit” be a gateway to addiction?  What’s the difference between addiction and physical dependence?  What’s going on with the brain’s dopaminergic systems during addictive behavior?  Tune in to find out.

Also in this episode, learn how to time your exercise routine to maximize your brain’s power to memorize.

Addiction or not, sometimes you just need a little bit more.  Keep up to date once-a-week on everything we’ve got going on… Sign up for our newsletter below.

Show Notes
  • 00:01:08

    Jesse gives us a lowdown on this week's episode.

  • 00:01:58

    This Week In Neuroscience: The relationship between the brain and the gut, before and after birth.

  • 00:03:54

    Thank you for the great reviews on iTunes.

  • 00:05:57

    A brand new way to sign up for the Smart Drug Smarts mailing list and keep your brain charged up with the latest in neuroscience.

  • 00:07:24

    Jesse introduces Dr. Jeremy Martinez.

  • 00:08:56

    Lesser known types of addiction and the distinction between physical dependence and addiction.

  • 00:13:02

    Discussion about Dopamine and addiction.

  • 00:15:42

    An interesting way to look at neurotransmitters and how drugs may affect them.

  • 00:17:03

    A study showing how exercise has positive effects on recovering addicts.

  • 00:18:14

    Jesse ruminates about the origin of Smart Drug Smarts and gives us an insight into his journey with this podcast.

  • 00:19:40

    Some of the more bizarre addictions that Dr. Jeremy Martinez has come across.

  • 00:21:31

    Can our favorite cognitive enhancers lead us down the addiction rabbit-hole?

  • 00:23:42

    The optimum method to determine whether you have a "problem" with a certain substance.

  • 00:25:20

    Dr. Martinez shares his insights about treating cocaine addiction.

  • 00:26:48

    Some hard-hitting advice from Dr. Martinez for those of us who are into cognitive enhancements

  • 00:30:12

    Ruthless Listener Retention Gimmick: When to time your exercise to get the best cognitive results.


  1. Cody says:

    I’d just like to respond to episode 80, where Dr Martinez says something about kratom leading to heroin use. In my experience (and most people on forums in the kratom community) is that kratom is used to abstain from heroin or other pharmaceutical opioids. It has had a lot of negative attention lately, but it can be a life saver. My sister went from a full blown heroin addiction: skin and bones, almost skeleton like, dope sick for days to a functional member of society using kratom. It’s been 3+ years now and the difference is amazing. She uses a steady daily amount to maintain a heroin free life. There is a mild dependency, but much less then buprenorphine, methadone or other maintenance treatments. There is a place for kratom, but i wish it wasn’t available in smoke shops, as it gives it a bad reputation. I have used kratom occasionally to ease depression and I can tell you that it’s uplifting but not a “high.” Comparable to a cup of coffee (coffee and kratom are similar, and in the same plant family I believe). I love the podcast and everything you guys do, just wanted to shed some light on a controversial subject. Feel free to contact me with any questions, I am very much willing to share more of the story.

    1. Jesse Lawler says:

      Thanks for the message, Cody. Sounds like a compound that deserves a closer look (reminds me of GHB as far as the “many sides to the story”). Interesting material for a future episode; we’ll see what we can do.

  2. Ali says:

    Jesse I feel like your voice sound like a robot, I think it’s the mic you’re using. can you check it next time?

    1. Jesse Lawler says:

      Hi Ahmed — That episode was a little over a year ago, so we’ve had a few “next times” since then. But yeah, mic problems can be annoying, and I apologize that some episodes’ sound comes out better than others. Normally the biggest issue we contend with is the recording quality of the mic/environment on the other end of the interview — but occasionally I’m the culprit. 🙂

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