Marijuana has been a hot topic since states like Colorado and Washington have legalized the plant. In the discussion surrounding marijuana, tetrahydrocannabinol (THC), the plant’s principal psychoactive cannabinoid, has gotten most of the limelight. But there’s another cannabinoid that deserves attention: Cannabidiol, also known as CBD.
Let’s get one thing clear right off the bat: Supplemental CBD is derived from industrial hemp, which is perfectly legal throughout the U.S. (unlike marijuana). It’s a close chemical analog to endocannabinoids, naturally occurring compounds within the human body, and it interacts with some of the same neuronal receptor-sites that the human body’s own endocannabinoids would interact with.
CBD vs. THC
There are more than 100 different cannabinoids in the marijuana plant; THC and CBD are just two of the major ones. THC rather famously enhances creativity, but can also make you paranoid and give you the munchies. CBD operates on different receptors than THC, and as you can imagine, it has dramatically different effects.
In fact, CBD decreases the psychoactive effects of THC without reducing THC’s ability to interact with the CB1 and CB2 receptors. That can mean less paranoia and fewer munchies, without reducing the creativity boost many people experience from THC.
What’s the big deal about CBD?
It would probably be easier to list what CBD doesn’t do. Ready for a (non-exhaustive) list of CBD’s capabilities? Take a deep breath…
CBD is antibacterial, anti-inflammatory, anti-anxiety, and neuroprotective. It functions as a sleep aid, reduces intestinal motility (think Irritable Bowel Syndrome), and blocks tumor growth. It also reduces the incidence of seizures in individuals with disorders like epilepsy, promotes bone re-growth in broken bones, and minimizes muscle cramps. And according to our interview guest, it even makes lucid dreams more likely.
Just say yes…
In episode 124, Jesse speaks with athlete and author Ben Greenfield about why CBD might be the star utility player missing from your medicine cabinet. Ben talks us through…
- Dosing for focus and relaxation vs. dosing for sleep
- Passing drug tests while taking CBD
- Methods of taking CBD (including…suppositories?)
- Contraindications and tolerance
- Bonus: Why you might want to avoid rubbing CBD oil on your body in an airplane
Listen in as Jesse chats with Ben, then check out Ben’s exhaustive post on taking CBD and his own hybrid-nanoengineered CBD oil extract supplements.
PS: Before you hop on the CBD bandwagon and get too relaxed, don’t forget to sign up for Brain Breakfast — weekly cognitive enhancement straight to your inbox.
Cannabidiol (or CBD for short)
This Week in Neuroscience: First paralysed person to be ‘reanimated’ offers neuroscience insights
The audience interaction section
Intro to Ben Greenfield and CBD
Other plants in the endocannabinoid family
The effects of CBD (can be found at ProjectCBD.org)
How CBD works inside our bodies and in conjunction with THC
“Weed shop” options expanding to include CBD
Pros and cons of different delivery methods
Vaping and its cerebral effects
CBD and absorbability
Optimal dosages for CBD and other supplements
Exercise and supplementation
Half-life of CBD
CBD and marijuana drug screening
CBD’s legal status in Canada
Are there any contraindications?
Cycling CBD and other supplements
Types of CBD extraction
Ruthless Listener-Retention Gimmick: Bicycle Day!