Episode 19

The Smart Drug Smarts podcast is back this week with a new self-experiment by Jesse as he records his own virgin voyage with Aniracetam.*  Aniracetam is the more-potent sibling chemical of Piracetam, with efficacy at the 750-1500 mg/day range, as opposed to Piracetam, which is generally considered to have 2400 mg/day as a bottom-end dosage.  In this episode, Jesse takes 750 mg of Aniracetam and documents his results. He also talks with his friend Ben about Ben’s experience using Modafinil for the first time.

*Aniracetam is a key ingredient in NEXUS, Axon Labs‘ flagship nootropic stack.

Aniracetam and its Benefits

Aniracetam is classified as an ampakine nootropic in the Racetam class. It is one of the more potent drugs in the class, and it’s gotten significant attention in Europe (including getting approved as a prescription pharmaceutical), but hasn’t been approved by the FDA in the United States.

Aniracetam has been reported to yield significant increases in cognitive functioning and abilities. This is further enhanced by its effects on memory recall and, probably more importantly, its high-level effects on learning. To add to that, the drug has been proven as an anxiolytic, a drug which helps reduce anxiety.

Reported side effects of Aniracetam vary widely, but the most commonly noted are insomnia, headaches, anxiety, pain, vertigo, nausea, and diarrhea. Many people report experiencing zero negative side-effects after taking a regular dose of Aniracetam, but the validity of these claims is definitely in question.

The standard recommended effective dose is 750 mg, but again, as with other aspects of the drug, this is widely debated.  Most forms of Aniracetam come in a 500 mg pill.

Jesse’s Effects

Following the common recommendations, Jesse swallows a 750 mg pill.  After only one hour, he starts to experience some subtle feelings of being on point and more focused.  At first, he notes that he’s not sure that it’s the drug, but it’s a feeling, nonetheless.

About two hours in, Jesse reports some interesting findings.  He recognizes that he’s feeling wired and restless.  He’s jumping from task to task, in what he calls a “multitasking frenzy.”  Although he doesn’t consider it bad, it’s at least weird, and worth noting.  Luckily, there’s no adverse effects on his appetite, as he’s chowing down on almonds while recording the episode.

Four and a half hours in and Jesse has big news. He feels that he’s sustained a high level of focus and interest in what he’s doing.  He’s not 100% convinced that it was the Aniracetam that caused the notably productive work session, but the results were significant enough that he calls the experiment a Round 1 success, and definitely worth giving another go in the near future.

This Week In Neuroscience: BBC News – Late Nights “Sap Children’s Brain Power’

Professor Amanda Sacker from University College London and her team conducted a study of the effects of sleep schedules on children’s minds. The test involved over 11,000 kids aged 3, 5, and 7 and showed interesting results.

Kids who went to bed earlier and at the same time nightly ended up scoring far higher on their math and reading tests. This might be caused by the disruption of the body’s natural rhythms, and because of this, it impairs the mind’s natural ability to learn and retain memory. The test did take into consideration the children’s home situations (more “organized” parents enforcing both bedtimes and better learning habits), but it’s tough to know if this confounding factor has been entirely mitigated.

Read the original article here.


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Written by Jesse Lawler
Jesse Lawler is a technologist, health nut, entrepreneur, and "one whose power switch defaults to On."  He created Smart Drug Smarts to learn how to make his brain do even more, and is greatly pleased to now see his little baby Frankenstein toddling around and helping others.  Jesse tweets about personal optimization, tech, and other stuff he finds interesting at @Lawlerpalooza.
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