Intermittent Fasting (IF) does seem to work differently for men versus women.

Unfortunately, there isn’t a ton of research to date that compares the differences, although there is one rat study and a few human trials exploring IF’s effect on women compared to men.

A couple of reputable health writers have combed the archives and written summaries about what is available:

The studies suggest that pre- and possibly perimenopausal women may respond to fasting with a stress response, negatively affecting their endocrine system.  What this means is that women might not get the benefits of IF (weight loss), and might even experience some negative health consequences, like amenorrhea and thyroid dysfunction.

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