Episode 39

In Episode #39, Jesse talks with Dr. Emily Deans on the subject of ketosis. Ketosis is a biological state that occurs during fasting or a low-carb dieting when glycogen stores in the liver are depleted. This causes the body to burn acetoacetate and β-hydroxybutyrate for fuel, instead of blood sugar. The effects of the “ketogenic state” go beyond kicking on the fat-burning furnace. Some people report a perception of higher cognitive function as well, and doctors have used ketosis to treat some otherwise unmanageable neurological disorders.

Emily Deans, M.D., is a board certified adult psychiatrist practicing in Massachusetts.  She graduated from the University of Texas Southwestern Medical School in 2000 and from the Harvard Longwood Psychiatry Residency in 2004, and was a Chief Resident at Brigham and Women’s Hospital in Boston.  She is currently a Clinical Instructor in Psychiatry at Harvard Medical school.

The overarching theory she explores is that our bodies and brains do best in the conditions for which they evolved.  She feels that by studying evolutionary medicine, we come closer to answers regarding the optimal conditions for health and vitality.

Dr. Deans’ “Don’ts”

Don’t eat very much fructose, omega-6 rich industrial vegetable oils, grains (such as wheat, rye, barley, spelt, quinoa, oats, corn, etc.), or processed “fake” food in general.

Dr. Deans’ “Dos”

Eat as much local, farm stand, grass-fed, pastured, wild-caught as you care for.  That’s vegetables, meat, fish, nuts, eggs, and fruits.

In Dr. Deans’ opinion, if you have no serious medical conditions, it’s perfectly healthy to have high-fat dairy, safe starches such as white rice or potatoes, red wine, and dark chocolate in moderation.

This Week In Neuroscience: Psilocybin Found to Inhibit Negative Emotions

Researchers at the Psychiatric University Hospital of Zurich have found that psilocybin, the psychoactive component found in magic mushrooms, can affect the amygdala and weaken the processing of negative emotions – like sadness, fear, anger and depression. Using Functional Magnetic Resonance Imaging (fMRI), researchers found that psilocybin stimulates production of serotonin in the limbic brain region, providing a “mood-brightening effect.” This is a significant finding, specifically in the area of research related to depression and anxiety disorders.

This leading-edge research is extremely important and, unfortunately (as we learned from our interview with Dr. David Nutt) still politically controversial. Here at Smart Drug Smarts, we take our collective hat off to the folks at the Psychiatric Hospital of Zurich, who forge undaunted into the taboo reaches of psychopharmacology in search of answers.

Read the original article here.

What You’ll Learn

  • What are ketones and what is ketosis
  • The minimum amount of glucose required to power your brain
  • How to safely experiment with ketosis
  • Ancestral man and seasonal ketosis
  • How ketosis is being used to treat brain trauma and emotional disorders


Key Terms Mentioned

Written by Ben Pomeroy
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