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Smart Drugs

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Here we dive into the nitty-gritty details of various smart drugs. 

What’s the difference between "nootropics" and "cognitive enhancers"?  What mechanism of action creates a certain effect in our brains?  How safe are different smart drugs?  Do they really work?

Here are few of our favorites:

And check out the list below for the best of the rest...


Join Jesse & attorney Lawrence Walters for an in-depth look at the gray market for pharmaceuticals – the regulations and risks involved to health and privacy.


Can “motivational” chemicals reduce people’s inherent laziness about exercise, and make them form better health habits? Tune in and find out.


In episode #98 Jesse throws four prescribed Adderall users into the mix who talk about their experiences with the drug and weigh the pros and cons.


What are Nootropics? There’s a lot of confusion surrounding nootropics and cognitive enhancers.  The two terms are often used interchangeably, but if you want to get really technical about it — and let’s face it, we do — then nootropic refers only to a narrow category of cognitive enhancing supplements. A substance must meet five tough …


I was the Cognitive-Enhancement Wild Man, the one whom the conservative members of the KCRW audience were giving dirty looks through their radios, while I waved my pom-poms for these so-called smart drugs.


Join Jesse and abelard Lindsay in a freewheeling discussion about the framework behind the nootropic stack Nexus – a flagship product of Axonlabs.io


Jesse takes Ritalin for the first time ever and conducts a single-subject scientific study. What results does the experiment yield? Tune in to find out.


Jesse and long-time biohacker and self-professed nootropics geek Abelard Lindsay take a look at how the recently launched Mitogen stack was born.


Jesse is joined by cave-diver-cum-research-scientist Dr. Dawn Kernagis from IHMC (the Florida Institute for Human and Machine Cognition) for a chat about maintaining optimal cognition in extreme environments.

Axon Labs

I decided I wanted Smart Drug Smarts to create products of its own — things that I wanted, I would use, I would trust, and I could fully endorse — from the standpoint of sound science, and also of safe, rigorously-tested manufacturing processes.

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