Smart Drugs

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Here we dive into the nitty-gritty details of various smart drugs. What’s the difference between “nootropics” and “cognitive enhancers”? What mechanism of action creates a certain effect in our brains? How safe are different smart drugs? Do they really work?


Here are few of our favorites:
And check out the list below for the best of the rest.


Abelard-Lindsay-mitogen-Mitochondrial

Jesse and long-time biohacker and self-professed nootropics geek Abelard Lindsay take a look at how the recently launched Mitogen stack was born.

x-brains-optimal-cognition-extreme-environments

Jesse is joined by cave-diver-cum-research-scientist Dr. Dawn Kernagis from IHMC (the Florida Institute for Human and Machine Cognition) for a chat about maintaining optimal cognition in extreme environments.

Axon Labs

I decided I wanted Smart Drug Smarts to create products of its own — things that I wanted, I would use, I would trust, and I could fully endorse — from the standpoint of sound science, and also of safe, rigorously-tested manufacturing processes.

Aniracetam-first-ampakines

Jesse has an insightful discussion about Aniracetam with Prof. Keith Wesnes responsible for almost 200 clinical trials in a career starting from 1970.

new-normal

You, me, and everyone we know, falls under this impending, theoretical threat.  Even those of us who are using cognitive enhancers (those currently available) — we’re still a part of the “home team,” compared to those upgraded rascals from 2020, or 2030, or 2045, and whatever brain-enhancers they’re  using to eventually disenfranchise the biological “normals.”

Slippery-Slopes-smart-drug-addiction

Could a smart drug “habit” be a gateway to addiction? What’s the difference between addiction and physical dependence? What’s going on with the brain’s dopaminergic systems during addictive behavior?

Phosphadytlserine-young-brain

Want to get more of a cognitive boost out of your workout? “Generally Recognised As Safe” supplement phosphatidylserine could be the answer.

Pycnogenol-Pine-Trees

This week Jesse and Dr. Jeffry Strong wander into a forest of lesser known plant extracts, discussing Pycnogenol, a product derived from the bark of a unique species of pine trees. Its effects range from anti-oxidation and reduction of inflammation to circulatory-system and cognitive improvements. One theory to Pycnogenol’s success is that it has a …

fish-oil-cognitive-lubricant

Jesse is joined by Dr. Andrew Pipingas and Professor David Crewther for a conversation about fish oil and its effects on neural efficiency, introducing the idea that “smart brains work less hard.”

Lemon-Balm

Professor Andrew Scholey takes us through the history and effects of adaptogen, and powerful cognitive and mood enhancer Lemon Balm.

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