Dr. James Wilson Discusses Adrenal Fatigue


In episode #33, Jesse interviews Dr. James Wilson on the topic of topic of adrenal fatigue. In 1998, Dr. Wilson coined the term “adrenal fatigue” to identify below-optimal adrenal function (mostly resulting from stress) and distinguish it from Addison’s Disease.  However, after more than 15 years, not everyone in the medical community believes adrenal fatigue […]

Dr. Michael Lewis Discusses the Power of Omega-3 Fatty Acids


Dr. Michael Lewis discusses the positive impacts Omega-3 fatty acids can have on the health and maintenance of the human brain.

Mark Divine Discusses Mental Toughness and the Navy SEALs


Mark is the author of several books: 8 Weeks to SEALFIT, Way of the SEAL, and Unbeatable Mind. SEALFIT — a personal-improvement regimen developed by Mark — is uniquely effective at developing elite level physical and mental fitness, helping trainees to operate at an entirely new level in mental toughness, creative problem solving, leadership, team effectiveness and awareness.

Dr. Terry Wahls’ Functional-Medicine Diet: The Wahls Protocol

Dr. Terry Wahls

Dr. Wahls discusses her personal story of recovery from multiple sclerosis, her new book The Wahls Protocol, and the day-to-day choices that can extend your life, maximize your health and fend off the most common degenerative neurological diseases.

Dr. Laura Juliano Discusses Caffeine


In episode #26, Dr. Juliano speaks with Jesse about the nuances, dangers and benefits of caffeine — the world’s most popular and readily-available cognition-enhancing drug.

Dr. Gomez-Pinilla and the Impact of Diet and Exercise on Cognition


Dr. Gomez-Pinilla’s research is to investigate neuronal adaptation to environmental factors like diet — and how this scales up to the whole-organism level.

Dr. Raza Naqvi’s Review of 32 Published Pharmacological Studies


Dr. Naqvi advises his patients to get off of as many medications as possible, unless there is a proven upside — and especially if they are already on other medications with which their may be unknown interactions.

Dr. Terry Wahls Discusses Cognitive Rehabilitation from Neurological Disease


Dr. Terry Wahls has managed to significantly reduce Multiple Sclerosis’ impact on her life by self-experimentation, after a deep study of basic science research and animal-model neurological studies in mammals like mice.

Sebastian Marshall and the Quantified Self

Qualified Self Stats

Sebastian has methodically tested an impressive number of variables to determine their effects on his personal productivity and quality of life. From dairy products to smart drugs to the lighting in his sleep environment, he’s tested (and continues to re-test) contributing elements to his life and business, and the information in this episode may just make you want to crack open an Excel file and do the same.

Dr. Neal Barnard Advises a Plant-Based Diet

Dr. Neal Barnard

Dr. Barnard is a world-renowned nutrition expert and outspoken vegan, and the author of 15 books and host of three PBS television specials. He specializes in the effect people’s diets have on their bodies and brains, and their propensity for Alzheimer’s Disease and dementia.