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Neuroscience

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At the heart of cognitive enhancement is the study of the brain as a whole.

Here we cover topics that answer the question "How does this work?"  Things like memory, neurotransmitters, and what goes on inside aging brains.

Otherwise, scroll down and enjoy...

Episode 138 image

fMRI sounds pretty scientific, right? But it turns out that plenty of scientific results, backed by fMRI data, may be unreliable.

DMT with Dr. Rick Strassman

Dr. Rick Strassman is something of a legend in the psychedelic research community. His studies in the early 1990s re-opened a door which had been securely bolted for almost three decades: a prohibition against testing psychedelics on human research subjects.

Flynn Effect

Apologies for the ultra-brief post, but we wanted to get this Overdose Edition up quickly… The Flynn Effect is a strange-but-true revelation.  Over the course of the 20th century — and apparently continuing still — “average” people in countries around the world, as measured by standardized IQ tests, are getting smarter and smarter and smarter.  …

Autoimmunity Question & Answers with Dr. Terry Wahls

Practical Advice for Navigating Autoimmunity in Everyday Life In Episode 136, Dr. Terry Wahls shared the clinical results of her latest research.  Wahls herself is a walking testimonial to the effectiveness of the dietary changes now known as “the Wahls Protocol™” — and clinical research is currently providing further evidence to reinforce her recommendations. For those who experience the daily …

Attention-Schema Theory, consciousness, awareness, smart drugs, nootropics, neuroscience

In his book “Consciousness and the Social Brain,” Princeton neuroscientist Dr. Michael Graziano lays out his compelling Attention-Schema Theory. Has he solved the “Hard Problem” of Consciousness?

Intermittent Fasting, Cognition, Caloric Restriction, Fasting, nootropics

Dr. Mark Mattson, neurologist at Johns Hopkins University and the National Institute of Health (NIH), has decades of work in the fields of nutrition, brain health, and the complex interplay between diet, exercise, “feeding windows,” and macronutrient ratios. Join us in Episode #120 to learn his many insights.

turmeric, schizandra, adaptogens, nootropics, smart drugs

The adaptogen plant turmeric has been a mainstay of Indian and Asian cooking for millenia. Its root is chock-full of bioactive curcuminoid compounds that have been shown to provide wide-ranging benefits from the reduction of oxidative stress to the reduction of psychological stress.

lymphatic system, neuroscience, brain health

“Textbooks are going to need to change.” That was the general consensus around the 2015 discovery that previously unknown lymphatic vessels connect the brain directly to the immune system. Hear about the breakthrough discovery from co-discoverer Professor Jonathan Kipnis.

technology, prosthetics, biohacking, nootropics, smart drugs

“Grinders” take their stylistic queues from piercing shops, tattoo parlors and custom auto mechanics — combining skills in electrical circuitry and biology to leap past “wearable” technology straight into integrated doodads like an LED compass that lives in your hand, or under-the-skin magnets (which some claim allow them to “feel” magnetic fields after a few months of brain plasticity and practice).

smart drugs, nootropics, psilocybin, depression, mushrooms, addiction, PTSD, therapy

Dr. Frederick Barrett discusses recent and upcoming studies into psilocybin — the psychoactive ingredient that puts the “magic” in magic mushrooms.  This currently “Schedule 1” drug, in addition to reasonably reliably provoking mystical experiences in users, also shows promise as a therapeutic treatment for depression, PTSD, and hospice care.  Dr. Barrett and colleagues at Johns Hopkins Medical Center are at the forefront of the latest research.

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