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Omega-6 fatty acids are both essential and misunderstood — occasionally even demonized as a too-prevalent part of the Standard American Diet. Dr. Chris Masterjohn explains the role they fill in the human diet, and against-the-grain advice on how to acquire them with a minimum of fuss.

Music and the Brain

Music is something beloved of people everywhere — or at least, 98% of them (no joke – details within). Not surprisingly, music can provoke complex brain responses, both in terms of short term emotion and long-term learning and perceptual awareness. Join doctors Robert Zatorre and Assal Habibi to learn more from the cutting edge of neuroscience and musicology.


Lithium has long been a standard treatment for mania and Bipolar Disorder. But this might be only the tip of an iceberg of usefulness to human brains and bodies. Dr. De-Maw Chuang explains.

Had I just woken up? Or had I been awake? I was sure I was awake — although I couldn’t actually see anything. I also couldn’t feel anything.  That is, I literally couldn’t feel anything.  (And here I mean literally from back when literally meant “literally,” before literally started meaning “not literally, but figuratively.”) I …

Consanguineous Marriages

If your society allows consanguineous marriages (more to the point, cousins making babies with cousins) the genetic impact costs you almost 95% of the geniuses that random luck would have provided.

DMT with Dr. Rick Strassman

Dr. Rick Strassman is something of a legend in the psychedelic research community. His studies in the early 1990s re-opened a door which had been securely bolted for almost three decades: a prohibition against testing psychedelics on human research subjects.

Flynn Effect

Apologies for the ultra-brief post, but we wanted to get this Overdose Edition up quickly… The Flynn Effect is a strange-but-true revelation.  Over the course of the 20th century — and apparently continuing still — “average” people in countries around the world, as measured by standardized IQ tests, are getting smarter and smarter and smarter.  …

Attention-Schema Theory, consciousness, awareness, smart drugs, nootropics, neuroscience

In his book “Consciousness and the Social Brain,” Princeton neuroscientist Dr. Michael Graziano lays out his compelling Attention-Schema Theory. Has he solved the “Hard Problem” of Consciousness?

supplement, quality assurance, nootropics, smart drugs

LabDoor’s goal is full-spectrum testing of the majority of consumer supplements — upwards of 10,000 different products. One piece of their innovative approach is to have users vote on what category of supplements gets added to their next battery of tests.

Intermittent Fasting, Cognition, Caloric Restriction, Fasting, nootropics

Dr. Mark Mattson, neurologist at Johns Hopkins University and the National Institute of Health (NIH), has decades of work in the fields of nutrition, brain health, and the complex interplay between diet, exercise, “feeding windows,” and macronutrient ratios. Join us in Episode #120 to learn his many insights.

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